Back-stepping, hidden substeps, and conditional dwell times in molecular motors
نویسندگان
چکیده
منابع مشابه
Back-stepping, hidden substeps, and conditional dwell times in molecular motors.
Processive molecular motors take more-or-less uniformly sized steps, along spatially periodic tracks, mostly forwards but increasingly backwards under loads. Experimentally, the major steps can be resolved clearly within the noise but one knows biochemically that one or more mechanochemical substeps remain hidden in each enzymatic cycle. In order to properly interpret experimental data for back...
متن کاملDwell time symmetry in random walks and molecular motors.
The statistics of steps and dwell times in reversible molecular motors differ from those of cycle completion in enzyme kinetics. The reason is that a step is only one of several transitions in the mechanochemical cycle. As a result, theoretical results for cycle completion in enzyme kinetics do not apply to stepping data. To allow correct parameter estimation, and to guide data analysis and exp...
متن کاملCooperative molecular motors moving back and forth.
We use a two-state ratchet model to study the cooperative bidirectional motion of molecular motors on cytoskeletal tracks with randomly alternating polarities. Our model is based on a previously proposed model [Badoual, Proc. Natl. Acad. Sci. U.S.A. 99, 6696 (2002)] for collective motor dynamics and, in addition, takes into account the cooperativity effect arising from the elastic tension that ...
متن کاملControl of Stepping Motors
This tutorial covers the basic principles of stepping motors and stepping motor control systems, including both the physics of steppers, the electronics of the basic control systems, and software architectures appropriate for motor control.
متن کاملMicro-stepping for Stepper Motors
Stepper motor performance can be compromised by noise and vibration, but an advanced high-torque micro-stepping algorithm can minimise the impact of both noise and vibration as well as increasing the resolution of the rotations. The embedded microcontroller which hosts the micro-stepper algorithm also provides additional flexibility to integrate current-limiting as well as adjusting the drive c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physical Review E
سال: 2007
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.75.021909